Understand What 7-Hydroxymitragynine (7-OH) Is

In the case of naturally occurring compounds that can induce activity at the brain opioid receptors, the 7-hydroxymitragynine (also commonly abbreviated as 7-OH) has gained much attention. The compound, present in the plant Mitragyna speciosa (also referred to as kratom), is thought to be one of the major factors that enable kratom to have painkilling and mood-altering properties. However, what is the real comparison between 7-hydroxymitragynine and the traditional opioids such as morphine and what are the associated dangers? We shall investigate the science and safety of it.

What Is 7-Hydroxymitragynine (7-OH)?

An active alkaloid mitragynine 7-hydroxymitragynine is present in kratom leaves but in extremely low concentrations in comparison to the active constituent, mitragynine. When consumed, mitragynine has been found to actually be transformed to 7-hydroxymitragynine within the body, and therefore, it is more potent.

This chemical attaches itself to the same opioid receptors that morpheine or oxycodone attaches to in the brain, and this is why it has a pain relieving and euphoric effect. But using kratom and its derivatives, in contrast to conventional opioids, are based on plants and are not well comprehended in their long-term health impacts.

Due to its strong action on the central nervous system, 7-hydroxymitragynine has become an issue of concern among health experts. Even though there are individuals who consume kratom as a natural pain reliever or mood uplifter, its abuse may easily result in addiction, withdrawal and severe side effects.

How Strong Is 7-Hydroxymitragynine Compared to Morphine?

It has been asserted that 7-hydroxymitragynine may be multiple times more effective than morphine in the actions of stimulating opioid receptors. It has been shown that it can be as many as 13 times stronger in specific situations, but its consequences are related to dosage, preparation and individual tolerance.

Although such power can be discussed as helpful in terms of pain relief, it also implies that the risks of addiction, dependence, and side effects are high. Effects of 7-OH on the brain can be easily adjusted, which is why the users develop withdrawal symptoms upon attempting to stop its use.

Morphine, conversely, has an established medical history and known dosages and has standardized use in medical supervision, making it much more dangerous. 7-hydroxymitragynine, however, is readily available in unregulated kratom products with a range of different potency and purity, and is thus far more harmful.

Differences Between 7-Hydroxymitragynine and Morphine

Even though both substances target the opioid receptors of the brain, they do so differently;

• Source:

  • 7-hydroxymitragynine: This is a naturally occurring substance that is a product of the kratom leaves.

  • Morphine: This is an opioid that is derived and purified out of the opium poppy.

• Legality and Regulation:

  • Morphine is a prescription drug that is used in severe pain.

  • The 7-hydroxymitragynine, as kratom, is not prohibited in certain places but in others, based on safety concerns.

• Onset and Duration:

  • 7-OH is more likely to have brief and unpredictable effects with regard to the route of intake.

  • The effects of morphine are more predictable and it has set guidelines of dosing.

Side Effects, Withdrawal, and Safety Concerns

Both 7-hydroxymitragynine and morphine have severe side effects, including:

• Nausea, vertigo and constipation.

• Slowed breathing (respiratory depression).

• Sedation and confusion

• Physical dependence and tolerance.

The withdrawal effects are anxiety, muscle pain, irritability, insomnia, and intense cravings when an individual ceases to take kratom or other substances that resemble opioids.

Inability to be regulated is one of the biggest safety issues with 7-hydroxymitragynine. Since the purity and strength of kratom products may have extreme differences, the user is not aware of the fact that he/she might be taking very high amounts of this substance. This inconsistency raises the chances of the risk of overdose or toxicity, particularly in combination with other drugs.

Conclusion

Although 7-hydroxymitragynine can provide a short-term solution to pain or discomfort, its strength and the risk of addiction complicate this medication as an option to use in the long run. In the absence of medical advice, the risks usually overpower the perceived advantage.

In case of your or a loved one who is grappling with the addiction of kratom or opioid dependency, there is help. We offer evidence-based and compassionate care to substance use and mental health issues at Palm Coast Treatment Solutions. Our group assists people to safely detox, deal with withdrawal and initiate sustainable recovery.

Today, call us and become the first step to a healthier, drug-free life (386) 284-4151.